ASME TechCast: Redefining Nuclear Power with Caroline DeWitte, co-founder and COO of Oklo, Inc.

In this episode of ASME TechCast, Caroline DeWitte, co-founder and COO of Oklo,  explores how advanced reactor technologies are moving from promise to deployment and what it will take to deliver clean, reliable, and affordable energy at scale.  

DeWitte brings a multidisciplinary background to the discussion, combining experience in nuclear engineering, technology commercialization, startups, and energy innovation. She holds a master’s degree in nuclear engineering from MIT and bachelor's degrees in economics and mechanical engineering from the University of Oklahoma. She is currently the co-founder and COO of Oklo, an advanced nuclear company based in Santa Clara, California. 

The conversation examines Oklo’s Aurora powerhouse technology, the role of regulatory progress, and the business models needed to make advanced nuclear energy practical for customers that want clean power without owning or operating a reactor. DeWitte also shares how collaboration, humility, ownership, and pathfinding are helping Oklo turn breakthrough ideas into real-world solutions.